PDB entry 4y4l

View 4y4l on RCSB PDB site
Description: Crystal structure of yeast Thi4-C205S
Class: biosynthetic protein
Keywords: biosynthetic protein
Deposited on 2015-02-10, released 2016-03-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-03-09, with a file datestamp of 2016-03-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thiamine thiazole synthase
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: THI4, ESP35, MOL1, YGR144W, G6620
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32318
      • engineered mutation (224)
    Domains in SCOPe 2.06: d4y4la_
  • Chain 'B':
    Compound: Thiamine thiazole synthase
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: THI4, ESP35, MOL1, YGR144W, G6620
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32318 (Start-345)
      • engineered mutation (224)
    Domains in SCOPe 2.06: d4y4lb_
  • Chain 'C':
    Compound: Thiamine thiazole synthase
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: THI4, ESP35, MOL1, YGR144W, G6620
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32318
      • engineered mutation (224)
    Domains in SCOPe 2.06: d4y4lc_
  • Chain 'D':
    Compound: Thiamine thiazole synthase
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: THI4, ESP35, MOL1, YGR144W, G6620
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32318
      • engineered mutation (224)
    Domains in SCOPe 2.06: d4y4ld_
  • Heterogens: 48N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4y4lA (A:)
mgsshhhhhhssglvprgshmsatstatstsasqlhlnstpvthclsdivkkedwsdfkf
apirestvsramtsryfkdldkfavsdviivgagssglsaayviaknrpdlkvciiessv
apgggswlggqlfsamvmrkpahlflqeleipyedegdyvvvkhaalfistvlskvlqlp
nvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahgtqcsmdpnvielagykndg
trdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmkgldmnhaehdvvihsgay
agvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilkhfaa

    Sequence, based on observed residues (ATOM records): (download) 
    >4y4lA (A:)
vthclsdivkkedwsdfkfapirestvsramtsryfkdldkfavsdviivgagssglsaa
yviaknrpdlkvciiessvapgggswlggqlfsamvmrkpahlflqeleipyedegdyvv
vkhaalfistvlskvlqlpnvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahg
tcsmdpnvielagykndgtrdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmk
gldmnhaehdvvihsgayagvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilk
hfa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4y4lB (B:)
mgsshhhhhhssglvprgshmsatstatstsasqlhlnstpvthclsdivkkedwsdfkf
apirestvsramtsryfkdldkfavsdviivgagssglsaayviaknrpdlkvciiessv
apgggswlggqlfsamvmrkpahlflqeleipyedegdyvvvkhaalfistvlskvlqlp
nvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahgtqcsmdpnvielagykndg
trdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmkgldmnhaehdvvihsgay
agvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilkhfaa

    Sequence, based on observed residues (ATOM records): (download) 
    >4y4lB (B:)
vthclsdivkkedwsdfkfapirestvsramtsryfkdldkfavsdviivgagssglsaa
yviaknrpdlkvciiessvapgggswlggqlfsamvmrkpahlflqeleipyedegdyvv
vkhaalfistvlskvlqlpnvklfnatcvedlvtrpptvagvvtnwtlvtqahgtcsmdp
nvielagykndgtrdlsqkhgvilsttghdgpfgafcakrivdidnqklggmkgldmnha
ehdvvihsgayagvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilkhfaa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4y4lC (C:)
mgsshhhhhhssglvprgshmsatstatstsasqlhlnstpvthclsdivkkedwsdfkf
apirestvsramtsryfkdldkfavsdviivgagssglsaayviaknrpdlkvciiessv
apgggswlggqlfsamvmrkpahlflqeleipyedegdyvvvkhaalfistvlskvlqlp
nvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahgtqcsmdpnvielagykndg
trdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmkgldmnhaehdvvihsgay
agvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilkhfaa

    Sequence, based on observed residues (ATOM records): (download) 
    >4y4lC (C:)
thclsdivkkedwsdfkfapirestvsramtsryfkdldkfavsdviivgagssglsaay
viaknrpdlkvciiessvapgggswlggqlfsamvmrkpahlflqeleipyedegdyvvv
khaalfistvlskvlqlpnvklfnatcvedlvtrppgevtvagvvtnwtlvtqahgtcsm
dpnvielagykndgtrdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmkgldm
nhaehdvvihsgayagvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilkhfa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4y4lD (D:)
mgsshhhhhhssglvprgshmsatstatstsasqlhlnstpvthclsdivkkedwsdfkf
apirestvsramtsryfkdldkfavsdviivgagssglsaayviaknrpdlkvciiessv
apgggswlggqlfsamvmrkpahlflqeleipyedegdyvvvkhaalfistvlskvlqlp
nvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahgtqcsmdpnvielagykndg
trdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmkgldmnhaehdvvihsgay
agvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilkhfaa

    Sequence, based on observed residues (ATOM records): (download) 
    >4y4lD (D:)
vthclsdivkkedwsdfkfapirestvsramtsryfkdldkfavsdviivgagssglsaa
yviaknrpdlkvciiessvapgggswlggqlfsamvmrkpahlflqeleipyedegdyvv
vkhaalfistvlskvlqlpnvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahg
tcsmdpnvielagykndgtrdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmk
gldmnhaehdvvihsgayagvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilk
hfa