PDB entry 4xim

View 4xim on RCSB PDB site
Description: protein engineering of xylose (glucose) isomerase from actinoplanes missouriensis. 1. crystallography and site-directed mutagenesis of metal binding sites
Class: isomerase(intramolecular oxidoreductse)
Keywords: isomerase(intramolecular oxidoreductse)
Deposited on 1992-03-11, released 1993-07-15
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.158
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4xima_
  • Chain 'B':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ximb_
  • Chain 'C':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ximc_
  • Chain 'D':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ximd_
  • Heterogens: CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ximA (A:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >4ximA (A:)
qatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfgs
daqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrqm
dlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiepk
pneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklfh
idlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedydg
vwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrsa
fedydadavgakgfgfvklnqlaiehllgar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ximB (B:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >4ximB (B:)
qatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfgs
daqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrqm
dlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiepk
pneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklfh
idlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedydg
vwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrsa
fedydadavgakgfgfvklnqlaiehllgar

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ximC (C:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >4ximC (C:)
qatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfgs
daqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrqm
dlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiepk
pneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklfh
idlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedydg
vwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrsa
fedydadavgakgfgfvklnqlaiehllgar

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ximD (D:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >4ximD (D:)
qatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfgs
daqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrqm
dlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiepk
pneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklfh
idlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprhfdykpsrtedydg
vwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrsa
fedydadavgakgfgfvklnqlaiehllgar