PDB entry 4x7u

View 4x7u on RCSB PDB site
Description: MycF mycinamicin III 3'-O-methyltransferase in complex with Mg, SAH and mycinamicin III (substrate)
Class: Transferase/Antibiotic
Keywords: macrolide, methyltransferase, antibiotic, natural product, Transferase-Antibiotic complex
Deposited on 2014-12-09, released 2015-03-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-05-27, with a file datestamp of 2015-05-22.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mycinamicin III 3''-O-methyltransferase
    Species: Micromonospora griseorubida [TaxId:28040]
    Gene: mycF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4x7ua_
  • Chain 'B':
    Compound: Mycinamicin III 3''-O-methyltransferase
    Species: Micromonospora griseorubida [TaxId:28040]
    Gene: mycF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4x7ub_
  • Heterogens: MG, SAH, ZM3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x7uA (A:)
mgsshhhhhhssglvprgshmspstgvelyldllkrtvsnfiyqdathvagliteaafve
earesgedyptvahtmigmkrlnnlqhcvesalrdgvpgdvletgvwrggacifargilk
aydvrdrtvwvadsfqgfpkitdddhpmdaemnlhqyneavdlptslatvqrnfsrygll
ddqvrflpgwfkdtmptapferlavlrmdgdsygatmdvlthayprlspggfaiiddyci
pacreavheyrdrhgisdeiveidrqgvywrrsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4x7uA (A:)
pstgvelyldllkrtvsnfiyqdathvagliteaafveearesgedyptvahtmigmkrl
nnlqhcvesalrdgvpgdvletgvwrggacifargilkaydvrdrtvwvadsfqgfpkit
dddhpmdaemnlhqyneavdlptslatvqrnfsrygllddqvrflpgwfkdtmptapfer
lavlrmdgdsygatmdvlthayprlspggfaiiddycipacreavheyrdrhgisdeive
idrqgvywrrsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4x7uB (B:)
mgsshhhhhhssglvprgshmspstgvelyldllkrtvsnfiyqdathvagliteaafve
earesgedyptvahtmigmkrlnnlqhcvesalrdgvpgdvletgvwrggacifargilk
aydvrdrtvwvadsfqgfpkitdddhpmdaemnlhqyneavdlptslatvqrnfsrygll
ddqvrflpgwfkdtmptapferlavlrmdgdsygatmdvlthayprlspggfaiiddyci
pacreavheyrdrhgisdeiveidrqgvywrrsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4x7uB (B:)
pstgvelyldllkrtvsnfiyqdathvagliteaafveearesgedyptvahtmigmkrl
nnlqhcvesalrdgvpgdvletgvwrggacifargilkaydvrdrtvwvadsfqgfpkit
dddhpmdaemnlhqyneavdlptslatvqrnfsrygllddqvrflpgwfkdtmptapfer
lavlrmdgdsygatmdvlthayprlspggfaiiddycipacreavheyrdrhgisdeive
idrqgvywrrsa