PDB entry 4x45

View 4x45 on RCSB PDB site
Description: Crystal Structure of F173G Mutant of Human APRT
Class: transferase
Keywords: aprt, transferase
Deposited on 2014-12-02, released 2015-12-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-12-02, with a file datestamp of 2015-11-27.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Adenine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: APRT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07741 (Start-179)
      • engineered mutation (172)
    Domains in SCOPe 2.07: d4x45a_
  • Chain 'B':
    Compound: Adenine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: APRT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07741 (Start-179)
      • engineered mutation (172)
    Domains in SCOPe 2.07: d4x45b_
  • Heterogens: AMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x45A (A:)
madselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridy
iagldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepg
qrvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpgfsllqye

    Sequence, based on observed residues (ATOM records): (download) 
    >4x45A (A:)
adselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyi
agldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgq
rvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpgfsllqye

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4x45B (B:)
madselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridy
iagldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepg
qrvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpgfsllqye

    Sequence, based on observed residues (ATOM records): (download) 
    >4x45B (B:)
adselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyi
agldsrgflfgpslaqelglgcvlirkrgklpgptlwasyskaeleiqkdalepgqrvvv
vddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpgfsllqye