PDB entry 4wlf

View 4wlf on RCSB PDB site
Description: Crystal structure of L-malate bound MDH2
Class: oxidoreductase
Keywords: MDH2, TCA cycle, OXIDOREDUCTASE
Deposited on 2014-10-07, released 2015-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-11-25, with a file datestamp of 2015-11-20.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Malate dehydrogenase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wlfa1, d4wlfa2
  • Chain 'B':
    Compound: Malate dehydrogenase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wlfb1, d4wlfb2
  • Chain 'C':
    Compound: Malate dehydrogenase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wlfc1, d4wlfc2
  • Chain 'D':
    Compound: Malate dehydrogenase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: MDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wlfd1, d4wlfd2
  • Heterogens: LMR, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wlfA (A:)
mgsshhhhhhssglvprgshmsaqnnakvavlgasggigqplslllknsplvsrltlydi
ahtpgvaadlshietkaavkgylgpeqlpdclkgcdvvvipagvprkpgmtrddlfntna
tivatltaacaqhcpeamicvianpvnstipitaevfkkhgvynpnkifgvttldivran
tfvaelkgldparvnvpvigghagktiiplisqctpkvdfpqdqltaltgriqeagtevv
kakagagsatlsmayagarfvfslvdamngkegvvecsfvksqetectyfstplllgkkg
ieknlgigkvssfeekmisdaipelkasikkgedfvktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4wlfA (A:)
nakvavlgasggigqplslllknsplvsrltlydiahtpgvaadlshietkaavkgylgp
eqlpdclkgcdvvvipagvprkpgmtrddlfntnativatltaacaqhcpeamicvianp
vnstipitaevfkkhgvynpnkifgvttldivrantfvaelkgldparvnvpvigghagk
tiiplisqctpkvdfpqdqltaltgriqeagtevvkakagagsatlsmayagarfvfslv
damngkegvvecsfvksqetectyfstplllgkkgieknlgigkvssfeekmisdaipel
kasikkgedfvktl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4wlfB (B:)
mgsshhhhhhssglvprgshmsaqnnakvavlgasggigqplslllknsplvsrltlydi
ahtpgvaadlshietkaavkgylgpeqlpdclkgcdvvvipagvprkpgmtrddlfntna
tivatltaacaqhcpeamicvianpvnstipitaevfkkhgvynpnkifgvttldivran
tfvaelkgldparvnvpvigghagktiiplisqctpkvdfpqdqltaltgriqeagtevv
kakagagsatlsmayagarfvfslvdamngkegvvecsfvksqetectyfstplllgkkg
ieknlgigkvssfeekmisdaipelkasikkgedfvktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4wlfB (B:)
nakvavlgasggigqplslllknsplvsrltlydiahtpgvaadlshietkaavkgylgp
eqlpdclkgcdvvvipagvprkpgmtrddlfntnativatltaacaqhcpeamicvianp
vnstipitaevfkkhgvynpnkifgvttldivrantfvaelkgldparvnvpvigghagk
tiiplisqctpkvdfpqdqltaltgriqeagtevvkakagagsatlsmayagarfvfslv
damngkegvvecsfvksqetectyfstplllgkkgieknlgigkvssfeekmisdaipel
kasikkgedfvktl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4wlfC (C:)
mgsshhhhhhssglvprgshmsaqnnakvavlgasggigqplslllknsplvsrltlydi
ahtpgvaadlshietkaavkgylgpeqlpdclkgcdvvvipagvprkpgmtrddlfntna
tivatltaacaqhcpeamicvianpvnstipitaevfkkhgvynpnkifgvttldivran
tfvaelkgldparvnvpvigghagktiiplisqctpkvdfpqdqltaltgriqeagtevv
kakagagsatlsmayagarfvfslvdamngkegvvecsfvksqetectyfstplllgkkg
ieknlgigkvssfeekmisdaipelkasikkgedfvktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4wlfC (C:)
nakvavlgasggigqplslllknsplvsrltlydiahtpgvaadlshietkaavkgylgp
eqlpdclkgcdvvvipagvprkpgmtrddlfntnativatltaacaqhcpeamicvianp
vnstipitaevfkkhgvynpnkifgvttldivrantfvaelkgldparvnvpvigghagk
tiiplisqctpkvdfpqdqltaltgriqeagtevvkakagagsatlsmayagarfvfslv
damngkegvvecsfvksqetectyfstplllgkkgieknlgigkvssfeekmisdaipel
kasikkgedfvktl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4wlfD (D:)
mgsshhhhhhssglvprgshmsaqnnakvavlgasggigqplslllknsplvsrltlydi
ahtpgvaadlshietkaavkgylgpeqlpdclkgcdvvvipagvprkpgmtrddlfntna
tivatltaacaqhcpeamicvianpvnstipitaevfkkhgvynpnkifgvttldivran
tfvaelkgldparvnvpvigghagktiiplisqctpkvdfpqdqltaltgriqeagtevv
kakagagsatlsmayagarfvfslvdamngkegvvecsfvksqetectyfstplllgkkg
ieknlgigkvssfeekmisdaipelkasikkgedfvktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >4wlfD (D:)
nakvavlgasggigqplslllknsplvsrltlydiahtpgvaadlshietkaavkgylgp
eqlpdclkgcdvvvipagvprkpgmtrddlfntnativatltaacaqhcpeamicvianp
vnstipitaevfkkhgvynpnkifgvttldivrantfvaelkgldparvnvpvigghagk
tiiplisqctpkvdfpqdqltaltgriqeagtevvkakagagsatlsmayagarfvfslv
damngkegvvecsfvksqetectyfstplllgkkgieknlgigkvssfeekmisdaipel
kasikkgedfvktl