PDB entry 4w9s

View 4w9s on RCSB PDB site
Description: 2-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxypyrimidin-4(3H)-one bound to influenza 2009 H1N1 endonuclease
Class: transcription/transcription inhibitor
Keywords: cap-snatching, RNA binding protein, RNA binding protein-inhibitor complex
Deposited on 2014-08-27, released 2014-10-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-10-22, with a file datestamp of 2014-10-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.177
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus [TaxId:387207]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13166 (37-End)
      • expression tag (32-36)
      • conflict (121)
      • conflict (222)
    Domains in SCOPe 2.08: d4w9sa1, d4w9sa2
  • Heterogens: MN, SO4, 3K1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4w9sA (A:)
    mahhhhhhsrawrhpqfgghhhhhhalevlfqgplgsmedfvrqcfnpmivelaekamke
    ygedpkietnkfaaicthlevcfmysdfhfidergesiivesgdpnallkhrfeiiegrd
    rimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankiksekt
    hihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqsergeetvee
    r
    

    Sequence, based on observed residues (ATOM records): (download)
    >4w9sA (A:)
    gplgsmedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfhfid
    ergesiivesgdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydyken
    rfieigvtrrevhiyylekankiksekthihifsftgeematkadytldeesrariktrl
    ftirqemasrslwdsfrqse