PDB entry 4v2w

View 4v2w on RCSB PDB site
Description: JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H3K27me3 PEPTIDE (16-35)
Class: oxidoreductase
Keywords: jmjd2a, oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, double-stranded beta helix, dsbh, facial triad, demethylase, histone, jmjc domain, metal binding protein, epigenetic and transcription regulation, chromatin regulator, hydroxylation
Deposited on 2014-10-15, released 2014-11-26
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-11-26, with a file datestamp of 2014-11-21.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: 0.1742
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysine-specific demethylase 4a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4v2wa_
  • Chain 'B':
    Compound: lysine-specific demethylase 4a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4v2wb_
  • Chain 'C':
    Compound: Histone H3.1t
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NI, ZN, CL, OGA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4v2wA (A:)
mhhhhhhssgvdlgtenlyfqsmasesetlnpsarimtfyptmeefrnfsryiayiesqg
ahraglakvvppkewkprasyddiddlvipapiqqlvtgqsglftqyniqkkamtvrefr
kiansdkyctprysefeelerkywknltfnppiygadvngtlyekhvdewnigrlrtild
lvekesgitiegvntpylyfgmwktsfawhtedmdlysinylhfgepkswysvppehgkr
lerlakgffpgsaqsceaflrhkmtlisplmlkkygipfdkvtqeagefmitfpygyhag
fnhgfncaestnfatrrwieygkqavlcscrkdmvkismdvfvrkfqperyklwkagkdn
tvidhtlptpeaaeflkesel

    Sequence, based on observed residues (ATOM records): (download) 
    >4v2wA (A:)
tlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlv
ipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknlt
fnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfa
whtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlis
plmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlc
scrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaefl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4v2wB (B:)
mhhhhhhssgvdlgtenlyfqsmasesetlnpsarimtfyptmeefrnfsryiayiesqg
ahraglakvvppkewkprasyddiddlvipapiqqlvtgqsglftqyniqkkamtvrefr
kiansdkyctprysefeelerkywknltfnppiygadvngtlyekhvdewnigrlrtild
lvekesgitiegvntpylyfgmwktsfawhtedmdlysinylhfgepkswysvppehgkr
lerlakgffpgsaqsceaflrhkmtlisplmlkkygipfdkvtqeagefmitfpygyhag
fnhgfncaestnfatrrwieygkqavlcscrkdmvkismdvfvrkfqperyklwkagkdn
tvidhtlptpeaaeflkesel

    Sequence, based on observed residues (ATOM records): (download) 
    >4v2wB (B:)
sesetlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddi
ddlvipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkyw
knltfnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwk
tsfawhtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkm
tlisplmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkq
avlcscrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaeflk

  • Chain 'C':
    No sequence available.