PDB entry 4uai

View 4uai on RCSB PDB site
Description: Crystal structure of CXCL12 in complex with inhibitor
Class: cytokine/cytokine inhibitor
Keywords: CXCL12, inhibitor, complex, chemokine
Deposited on 2014-08-09, released 2014-11-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-12-03, with a file datestamp of 2014-11-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.186
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Stromal cell-derived factor 1
  Species: Homo sapiens [TaxId:9606]
  Gene: CXCL12, SDF1, SDF1A, SDF1B
  Database cross-references and differences (RAF-indexed):
  • Uniprot P48061 (0-67)
  Domains in SCOPe 2.06: d4uaia_
• Chain 'B':
  Compound: Stromal cell-derived factor 1
  Species: Homo sapiens [TaxId:9606]
  Gene: CXCL12, SDF1, SDF1A, SDF1B
  Database cross-references and differences (RAF-indexed):
  • Uniprot P48061 (Start-67)
  Domains in SCOPe 2.06: d4uaib_
• Heterogens: 3GG, SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4uaiA (A:)
  kpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqe
  ylekalnk
  

  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >4uaiB (B:)
  kpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqe
  ylekalnk
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4uaiB (B:)
  pvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqey
  lekalnk