PDB entry 4u4k

View 4u4k on RCSB PDB site
Description: Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors
Class: hormone receptor
Keywords: AR, agonist, HORMONE RECEPTOR
Deposited on 2014-07-23, released 2015-07-29
Made obsolete by 8e1a on 2016-04-13

The last revision prior to the SCOPe 2.06 freeze date was dated 2015-07-29, with a file datestamp of 2015-07-24.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Androgen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AR, DHTR, NR3C4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10275 (Start-276)
      • conflict (234)
    Domains in SCOPe 2.06: d4u4ka_
  • Heterogens: 3E0, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4u4kA (A:)
mgsshhhhhhssglvprgshmiegyecqpiflnvleaiepgvvcaghdnnqpdsfaalls
slnelgerqlvhvvkwakalpgfrnlhvddqmaviqyswmglmvfamgwrsftnvnsrml
yfapdlvfneyrmhksrmysqcvrmrhlsqefgwlqitpqeflcmkalllfsiipvdglk
nqkffdelrmnyikeldriiackrknptscsrrfyqltklldsvqpiarelhqfafdlli
kshmvsvdfpemmaeiisvqvpkilsgkvkpiyfhtq

    Sequence, based on observed residues (ATOM records): (download) 
    >4u4kA (A:)
qpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlh
vddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrh
lsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknp
tscsrrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsg
kvkpiyfhtq