PDB entry 4row

View 4row on RCSB PDB site
Description: The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA
Class: hydrolase
Keywords: Zinc Finger, DNA deamination, DNA Binding, deamination, HYDROLASE
Deposited on 2014-10-29, released 2014-12-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-02-17, with a file datestamp of 2016-02-12.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA dC->dU-editing enzyme APOBEC-3G
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC3G, MDS019
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC16 (6-End)
      • expression tag (3-5)
      • engineered mutation (183)
    Domains in SCOPe 2.07: d4rowa1, d4rowa2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rowA (A:)
gshmaslrhsmdpptftfnfnnepwvrgrhetylcyevermhndtwvllnqrrgflcnqa
phkhgflegrhaelcfldvipfwkldldqdyrvtcftswspcfscaqemakfisknkhvs
lciftariyddqgrcqeglrtlaeagakisimtysefkhcwdtfvdhqgcpfqpwdglde
hsqalsgrlrailqnqen

    Sequence, based on observed residues (ATOM records): (download) 
    >4rowA (A:)
maslrhsmdpptftfnfnnepwvrgrhetylcyevermhndtwvllnqrrgflcnqaphk
hgflegrhaelcfldvipfwkldldqdyrvtcftswspcfscaqemakfisknkhvslci
ftariyddqgrcqeglrtlaeagakisimtysefkhcwdtfvdhqgcpfqpwdgldehsq
alsgrlrailq