PDB entry 4qty

View 4qty on RCSB PDB site
Description: Caspase-3 E190A
Class: hydrolase/hydrolase inhibitor
Keywords: Allosteric networks, hydrolase-hydrolase inhibitor complex
Deposited on 2014-07-09, released 2014-11-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP3, CPP32
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42574 (0-248)
      • engineered mutation (161)
      • expression tag (249)
    Domains in SCOPe 2.07: d4qtya1, d4qtya2
  • Chain 'F':
    Compound: ace-asp-glu-val-asp-chloromethylketone inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 4QTY (Start-4)
  • Heterogens: NA, AZI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qtyA (A:)
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietdsgvdddmachkipvaadflyaystapgyyswrn
skdgswfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsm
ltkelyfyhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4qtyA (A:)
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgiethkipvaadflyaystapgyyswrnskdgswfiqs
lcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhh

  • Chain 'F':
    No sequence available.