PDB entry 4pnc

View 4pnc on RCSB PDB site
Description: e. coli methionine aminopeptidase in complex with inhibitor 7-methoxy-2-methylen-3,4-dihydronaphthalen-1(2h)-one
Class: hydrolase
Keywords: hydrolase(alpha-aminoacylpeptide), metal complex, methionine aminopeptidase, covalent inhibitor, 1-tetralone, hydrolase
Deposited on 2014-05-23, released 2014-07-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: 0.134
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionine aminopeptidase
    Species: Escherichia coli [TaxId:562]
    Gene: map, BN17_45901, BU34_07510, ECs0170, LF82_1274
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3TPN7
      • engineered mutation (174)
    Domains in SCOPe 2.06: d4pnca_
  • Heterogens: 7NP, CO, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pncA (A:)
maisiktpediekmrvagrlaaevlemiepyvkpgvstgeldricndyivneqhavsacl
gyhgypksvcisinevvchgipddakllkdgdivnidvtvikdgfhgdtskmfivgkpti
mgerlcritqeslylalrmvkpginlreigaaiqkfveaegfsvvreycghgigqgfhee
pqvlhydsretnvvlkpgmtftiepmvnagkkeirtmkdgwtvktkdrslsaqyehtivv
tdngceiltlrkddtipaiishde

    Sequence, based on observed residues (ATOM records): (download) 
    >4pncA (A:)
aisiktpediekmrvagrlaaevlemiepyvkpgvstgeldricndyivneqhavsaclg
yhgypksvcisinevvchgipddakllkdgdivnidvtvikdgfhgdtskmfivgkptim
gerlcritqeslylalrmvkpginlreigaaiqkfveaegfsvvreycghgigqgfheep
qvlhydsretnvvlkpgmtftiepmvnagkkeirtmkdgwtvktkdrslsaqyehtivvt
dngceiltlrkddtipaiishd