PDB entry 4pj6

View 4pj6 on RCSB PDB site
Description: Crystal Structure of Human Insulin Regulated Aminopeptidase with Lysine in Active Site
Class: hydrolase
Keywords: Aminopeptidase, Metalloprotease, Hydrolase
Deposited on 2014-05-12, released 2014-12-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leucyl-cystinyl aminopeptidase
    Species: Homo sapiens [TaxId:9606]
    Gene: LNPEP, OTASE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pj6a1, d4pj6a2, d4pj6a3, d4pj6a4
  • Chain 'B':
    Compound: Leucyl-cystinyl aminopeptidase
    Species: Homo sapiens [TaxId:9606]
    Gene: LNPEP, OTASE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pj6b1, d4pj6b2, d4pj6b3, d4pj6b4
  • Heterogens: ZN, LYS, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pj6A (A:)
satngklfpwaqirlptavvplryelslhpnltsmtfrgsvtisvqalqvtwniilhstg
hnisrvtfmsavssqekqaeileyayhgqiaivapeallaghnytlkieysanisssyyg
fygfsytdesnekkyfaatqfeplaarsafpcfdepafkatfiikiirdeqytalsnmpk
kssvvlddglvqdefsesvkmstylvafivgemknlsqdvngtlvsiyavpekigqvhya
lettvklleffqnyfeiqyplkkldlvaipdfeagamenwglltfreetllydsntssma
drklvtkiiahelahqwfgnlvtmkwwndlwlnegfatfmeyfslekifkelssyedfld
arfktmkkdslnsshpisssvqsseqieemfdslsyfkgsslllmlktylsedvfqhavv
lylhnhsyasiqsddlwdsfnevtnqtldvkrmmktwtlqkgfplvtvqkkgkelfiqqe
rfflnmkpeiqpsdtsylwhiplsyvtegrnyskyqsvslldkksgvinlteevlwvkvn
inmngyyivhyadddwealihqlkinpyvlsdkdranlinnifelaglgkvplkrafdli
nylgnenhtapitealfqtdliynlleklgymdlasrlvtrvfkllqnqiqqqtwtdegt
psmrelrsallefacthnlgncsttamklfddwmasngtqslptdvmttvfkvgaktdkg
wsfllgkyisigseaeknkilealassedvrklywlmksslngdnfrtqklsfiirtvgr
hfpghllawdfvkenwnklvqkfplgsytiqnivagstylfstkthlsevqaffenqsea
tfrlrcvqealeviqlniqwmeknlksltwwl

    Sequence, based on observed residues (ATOM records): (download) 
    >4pj6A (A:)
klfpwaqirlptavvplryelslhpnltsmtfrgsvtisvqalqvtwniilhstghnisr
vtfmsvssqekqaeileyayhgqiaivapeallaghnytlkieysanisssyygfygfsy
tdesnekkyfaatqfeplaarsafpcfdepafkatfiikiirdeqytalsnmpkkssvvl
ddglvqdefsesvkmstylvafivgemknlsqdvngtlvsiyavpekigqvhyalettvk
lleffqnyfeiqyplkkldlvaipdfeagamenwglltfreetllydsntssmadrklvt
kiiahelahqwfgnlvtmkwwndlwlnegfatfmeyfslekifkelssyedfldarfktm
kkdslnsshpisssvqsseqieemfdslsyfkgsslllmlktylsedvfqhavvlylhnh
syasiqsddlwdsfnevtnqtldvkrmmktwtlqkgfplvtvqkkgkelfiqqerfflnm
sdtsylwhiplsyvtegrnyskyqsvslldkksgvinlteevlwvkvninmngyyivhya
dddwealihqlkinpyvlsdkdranlinnifelaglgkvplkrafdlinylgnenhtapi
tealfqtdliynlleklgymdlasrlvtrvfkllqnqiqqqtwtdegtpsmrelrsalle
facthnlgncsttamklfddwmasngtqslptdvmttvfkvgaktdkgwsfllgkyisig
seaeknkilealassedvrklywlmksslngdnfrtqklsfiirtvgrhfpghllawdfv
kenwnklvqkfplgsytiqnivagstylfstkthlsevqaffenqseatfrlrcvqeale
viqlniqwmeknlksltwwl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pj6B (B:)
satngklfpwaqirlptavvplryelslhpnltsmtfrgsvtisvqalqvtwniilhstg
hnisrvtfmsavssqekqaeileyayhgqiaivapeallaghnytlkieysanisssyyg
fygfsytdesnekkyfaatqfeplaarsafpcfdepafkatfiikiirdeqytalsnmpk
kssvvlddglvqdefsesvkmstylvafivgemknlsqdvngtlvsiyavpekigqvhya
lettvklleffqnyfeiqyplkkldlvaipdfeagamenwglltfreetllydsntssma
drklvtkiiahelahqwfgnlvtmkwwndlwlnegfatfmeyfslekifkelssyedfld
arfktmkkdslnsshpisssvqsseqieemfdslsyfkgsslllmlktylsedvfqhavv
lylhnhsyasiqsddlwdsfnevtnqtldvkrmmktwtlqkgfplvtvqkkgkelfiqqe
rfflnmkpeiqpsdtsylwhiplsyvtegrnyskyqsvslldkksgvinlteevlwvkvn
inmngyyivhyadddwealihqlkinpyvlsdkdranlinnifelaglgkvplkrafdli
nylgnenhtapitealfqtdliynlleklgymdlasrlvtrvfkllqnqiqqqtwtdegt
psmrelrsallefacthnlgncsttamklfddwmasngtqslptdvmttvfkvgaktdkg
wsfllgkyisigseaeknkilealassedvrklywlmksslngdnfrtqklsfiirtvgr
hfpghllawdfvkenwnklvqkfplgsytiqnivagstylfstkthlsevqaffenqsea
tfrlrcvqealeviqlniqwmeknlksltwwl

    Sequence, based on observed residues (ATOM records): (download) 
    >4pj6B (B:)
lfpwaqirlptavvplryelslhpnltsmtfrgsvtisvqalqvtwniilhstghnisrv
tfmekqaeileyayhgqiaivapeallaghnytlkieysanisssyygfygfsytdesne
kkyfaatqfeplaarsafpcfdepafkatfiikiirdeqytalsnmpkkssvvlddglvq
defsesvkmstylvafivgemknlsqdvngtlvsiyavpekigqvhyalettvklleffq
nyfeiqyplkkldlvaipdfeagamenwglltfreetllydsntssmadrklvtkiiahe
lahqwfgnlvtmkwwndlwlnegfatfmeyfslekifkelssyedfldarfktmkkdsln
sshpisssvqsseqieemfdslsyfkgsslllmlktylsedvfqhavvlylhnhsyasiq
sddlwdsfnevtnqtldvkrmmktwtlqkgfplvtvqkkgkelfiqqerfflntsylwhi
plsyvtenyskyqsvslldkksgvinlteevlwvkvninmngyyivhyadddwealihql
kinpyvlsdkdranlinnifelaglgkvplkrafdlinylgnenhtapitealfqtdliy
nlleklgymdlasrlvtrvfkllqnqiqqqtwtdegtpsmrelrsallefacthnlgncs
ttamklfddwmasngtqslptdvmttvfkvgaktdkgwsfllgkyisigseaeknkilea
lassedvrklywlmksslngdnfrtqklsfiirtvgrhfpghllawdfvkenwnklvqkf
plgsytiqnivagstylfstkthlsevqaffenqseatfrlrcvqealeviqlniqwmek
nlksltwwl