PDB entry 4phl

View 4phl on RCSB PDB site
Description: TbrPDEB1-inhibitor complex
Class: Hydrolase/Hydrolase Inhibitor
Keywords: phosphodiesterase, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2014-05-06, released 2015-05-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Class 1 phosphodiesterase PDEB1
    Species: Trypanosoma brucei [TaxId:5691]
    Gene: PDEB1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WQX9
      • conflict (190)
    Domains in SCOPe 2.08: d4phla_
  • Chain 'B':
    Compound: Class 1 phosphodiesterase PDEB1
    Species: Trypanosoma brucei [TaxId:5691]
    Gene: PDEB1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WQX9 (Start-346)
      • conflict (190)
    Domains in SCOPe 2.08: d4phlb_
  • Heterogens: ZN, MG, PIL, GAI, GOL, EOH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4phlA (A:)
hmasknvpsravkrvtaitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaai
ayrlllgsglpqkfgcsdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvy
ekltelecfvllitalvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlave
ilsdpesdvfgglegaertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhr
mtmeiilkagdisnvtkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmela
kgqigfidfvaapffqkivdaclqgmqwtvdriksnraqwervletr

    Sequence, based on observed residues (ATOM records): (download) 
    >4phlA (A:)
taitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaaiayrlllgsglpqkfg
csdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvyekltelecfvllita
lvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlaveilsdpesdvfggleg
aertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhrmtmeiilkagdisnv
tkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmelakgqigfidfvaapff
qkivdaclqgmqwtvdriksnraqwervle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4phlB (B:)
hmasknvpsravkrvtaitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaai
ayrlllgsglpqkfgcsdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvy
ekltelecfvllitalvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlave
ilsdpesdvfgglegaertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhr
mtmeiilkagdisnvtkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmela
kgqigfidfvaapffqkivdaclqgmqwtvdriksnraqwervletr

    Sequence, based on observed residues (ATOM records): (download) 
    >4phlB (B:)
taitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaaiayrlllgsglpqkfg
csdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvyekltelecfvllita
lvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlaveilsdpesdvfggleg
aertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhrmtmeiilkagdisnv
tkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmelakgqigfidfvaapff
qkivdaclqgmqwtvdriksnraqwervletr