PDB entry 4pce

View 4pce on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with compound B13
Class: Transcription/transcription Inhibitor
Keywords: Transcription-transcription Inhibitor complex
Deposited on 2014-04-15, released 2014-05-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-06-04, with a file datestamp of 2014-05-30.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: 0.138
AEROSPACI score: 0.71 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.04: d4pcea_
• Heterogens: EDO, 2N0, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4pceA (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee