PDB entry 4p0w

View 4p0w on RCSB PDB site
Description: Human farnesyl diphosphate synthase in complex with Arenarone and zoledronate
Class: transferase
Keywords: FPPS, Inhibitor, Complex, Prenyl Synthase, TRANSFERASE
Deposited on 2014-02-23, released 2014-07-02
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-07-02, with a file datestamp of 2014-06-27.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: 0.208
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: farnesyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: FDPS, FPS, KIAA1293
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4p0wa_
  • Heterogens: 1XH, ZOL, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4p0wA (A:)
nsdvyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvv
vafrelveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvg
ldaindanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdl
vrftekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddy
ldlfgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkaly
eeldlpavflqyeedsyshimalieqyaaplppavflglarkiykrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >4p0wA (A:)
dvyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvva
frelveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgld
aindanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvr
ftekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyld
lfgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyee
ldlpavflqyeedsyshimalieqyaaplppavflglarkiykrrk