PDB entry 4osp

View 4osp on RCSB PDB site
Description: The crystal structure of urdamycin C-6 ketoreductase domain UrdMred with bound NADP and rabelomycin
Class: Oxidoreductase/Antibiotic
Keywords: Rossman fold, ketoreductase, NADPH binding, Oxidoreductase-Oxidoreductase inhibitor complex, Oxidoreductase-Antibiotic complex
Deposited on 2014-02-13, released 2014-10-01
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.197
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Oxygenase-reductase
    Species: Streptomyces fradiae [TaxId:1906]
    Gene: urdM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ospa_
  • Chain 'B':
    Compound: Oxygenase-reductase
    Species: Streptomyces fradiae [TaxId:1906]
    Gene: urdM
    Database cross-references and differences (RAF-indexed):
    • Uniprot K0IB23 (11-262)
      • expression tag (10)
  • Chain 'C':
    Compound: Oxygenase-reductase
    Species: Streptomyces fradiae [TaxId:1906]
    Gene: urdM
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Oxygenase-reductase
    Species: Streptomyces fradiae [TaxId:1906]
    Gene: urdM
    Database cross-references and differences (RAF-indexed):
    • Uniprot K0IB23 (11-262)
      • expression tag (10)
  • Heterogens: NAP, 2V4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ospA (A:)
mahhhhhhhrsgkltgktalvtgssrgigratairlaregalvavhcsrnreaadetvat
iekeggrafsvlaelgvpgdvhelflalerglkertdattldilvnnagvmggvapeevt
pelfdrlvavnakapffivqraltlipdggriinissgltrfanpqevayamtkgamdql
tlhfakhlgsrnitvnsvgpgitnngtpvfdnpeavaqmagysvfnrvgevtdvadvvaf
lagddarwitgsyldasggtllg

    Sequence, based on observed residues (ATOM records): (download) 
    >4ospA (A:)
gkltgktalvtgssrgigratairlaregalvavhcsrnreaadetvatiekeggrafsv
laelgvpgdvhelflalerglkertdattldilvnnagvmggvapeevtpelfdrlvavn
akapffivqraltlipdggriinissgltrfanpqevayamtkgamdqltlhfakhlgsr
nitvnsvgpgitnngtpvfdnpeavaqmagysvfnrvgevtdvadvvaflagddarwitg
syldasggtllg

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.