PDB entry 4ofb

View 4ofb on RCSB PDB site
Description: Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Class: protein binding
Keywords: BRCT domain, DSB DNA damage repair, non-phosphorylated peptide, PROTEIN BINDING
Deposited on 2014-01-14, released 2015-04-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-05-27, with a file datestamp of 2015-05-22.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: breast cancer type 1 susceptibility protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BRCA1, RNF53
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4ofba1, d4ofba2
  • Chain 'B':
    Compound: nonphosphopeptide inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 4OFB

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ofbA (A:)
vnkrmsmvvsgltpeefmlvykfarkhhitltnliteetthvvmktdaefvcertlkyfl
giaggkwvvsyfwvtqsikerkmlnehdfevrgdvvngrnhqgpkraresqdrkifrgle
iccygpftnmptdqlewmvqlcgasvvkelssftlgtgvhpivvvqpdawtedngfhaig
qmceapvvtrewvldsvalyqcqeldtylipqip

    Sequence, based on observed residues (ATOM records): (download) 
    >4ofbA (A:)
rmsmvvsgltpeefmlvykfarkhhitltnliteetthvvmktdaefvcertlkyflgia
ggkwvvsyfwvtqsikerkmlnehdfevrgdvvngrnhqgpkraresqdrkifrgleicc
ygpftnmptdqlewmvqlcgasvvkelssftlgtgvhpivvvqpdawtngfhaigqmcea
pvvtrewvldsvalyqcqeldtylipqip

  • Chain 'B':
    No sequence available.