PDB entry 4o9v

View 4o9v on RCSB PDB site
Description: Crystal structure of matriptase in complex with inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: MATRIPTASE, Trypsin-like serine proteinase fold, Protease, Small molecule inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-01-03, released 2014-05-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-05-28, with a file datestamp of 2014-05-23.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.174
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Suppressor of tumorigenicity 14 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: ST14, PRSS14, SNC19, TADG15
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4o9va_
  • Chain 'B':
    Compound: Peptide CGLR
    Species: Homo sapiens [TaxId:9606]
    Gene: ST14, PRSS14, SNC19, TADG15
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NT4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4o9vA (A:)
    vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
    flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpiclpd
    ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
    sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
    v
    

  • Chain 'B':
    No sequence available.