PDB entry 4o71
View 4o71 on RCSB PDB site
Description: Crystal structure of the first bromodomain of human BRD4 in complex with FLAVOPIRIDOL
Class: transcription/inhibitor
Keywords: BROMODOMAIN, CAP, HUNK1, MCAP, PROTEIN BINDING-INHIBITOR COMPLEX, MITOTIC CHROMOSOME ASSOCIATED PROTEIN, CELL CYCLE, INHIBITOR, TRANSCRIPTION-INHIBITOR complex
Deposited on
2013-12-24, released
2014-03-05
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-03-19, with a file datestamp of
2014-03-14.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: 0.137
AEROSPACI score: 0.68
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4o71a_ - Chain 'B':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4o71b_ - Heterogens: CPB, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4o71A (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4o71B (B:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee