PDB entry 4no7

View 4no7 on RCSB PDB site
Description: Human Glucokinase in complex with a nanomolar activator.
Class: transferase/transferase activator
Keywords: Kinase, pancreas, TRANSFERASE-TRANSFERASE ACTIVATOR complex
Deposited on 2013-11-19, released 2014-10-29
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-10-29, with a file datestamp of 2014-10-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.191
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35557 (16-End)
      • expression tag (9-15)
    Domains in SCOPe 2.04: d4no7a1, d4no7a2
  • Heterogens: GLC, 2N8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4no7A (A:)
mghhhhhhenlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasv
kmlptyvrstpegsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedam
tgtaemlfdyisecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasg
aegnnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacym
eemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekligg
kymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstl
glrpsttdcdivrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvykl
hpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4no7A (A:)
nlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrs
tpegsevgdflsldlggtnfrvmlvkvsvktkhqmysipedamtgtaemlfdyisecisd
fldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaikrr
gdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegrmc
vntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlvde
nllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrrace
svstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrltp
sceitfieseegsgrgaalvsavack