PDB entry 4n6l

View 4n6l on RCSB PDB site
Description: Crystal structure of human cystatin E/M
Class: hydrolase inhibitor
Keywords: cysteine protease inhibitor, legumain, asparaginyl endopeptidase, reactive center loop, papain, cathepsin, cancer, cystatin fold, protease inhibitor, HYDROLASE INHIBITOR
Deposited on 2013-10-14, released 2015-02-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cystatin-M
    Species: Homo sapiens [TaxId:9606]
    Gene: CST6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15828 (Start-122)
      • expression tag (123)
    Domains in SCOPe 2.07: d4n6la1, d4n6la2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4n6lA (A:)
mdrpqermvgelrdlspddpqvqkaaqaavasynmgsnsiyyfrdthiikaqsqlvagik
yfltmemgstdcrktrvtgdhvdlttcplaagaqqeklrcdfevlvvpwqnssqllkhnc
vqmlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4n6lA (A:)
qermvgelrdlspddpqvqkaaqaavasynmgsnsiyyfrdthiikaqsqlvagikyflt
memgstdcrktvdlttcplaagaqqeklrcdfevlvvpwqnssqllkhncvqml