PDB entry 4n1z

View 4n1z on RCSB PDB site
Description: Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1222
Class: transferase
Keywords: Alpha fold, synthase, ionization, dephosphorylation, cytosol, TRANSFERASE
Deposited on 2013-10-04, released 2014-12-10
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.206
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'F':
    Compound: farnesyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: FDPS, FPS, KIAA1293
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4n1zf_
  • Heterogens: PO4, MG, N1Z, HOH

PDB Chain Sequences:

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4n1zF (F:)
nsdvyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvv
vafrelveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvg
ldaindanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdl
vrftekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddy
ldlfgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkaly
eeldlpavflqyeedsyshimalieqyaaplppavflglarkiykrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >4n1zF (F:)
vyaqekqdfvqhfsqivrvlthpeigdaiarlkevleynaiggkynrgltvvvafrelve
prkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldaindan
lleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnlvrftekryks
ivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdpsvt
gkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlpavfl
qyeedsyshimalieqyaaplppavflglarki