PDB entry 4mng

View 4mng on RCSB PDB site
Description: Structure of the DP10.7 TCR with CD1d-sulfatide
Class: immune system
Keywords: Immunglobulin, Histocompatibility Antigens, CD1, Immunological, lymphocytes, gamma delta T cell, T cell recognition, self-recognition, myelin, intestinal epithelial lymphocytes, Human, Lipid binding, self-ligand, Glycoproteins, Cell-surface receptors, IMMUNE SYSTEM
Deposited on 2013-09-10, released 2013-12-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-06-14, with a file datestamp of 2017-06-09.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cd1d1 protein
    Species: Mus musculus [TaxId:10090]
    Gene: Cd1d1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15813 (Start-183)
    • Uniprot Q7TMK5 (184-277)
      • expression tag (278)
    Domains in SCOPe 2.07: d4mnga1, d4mnga2, d4mnga3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Mus musculus [TaxId:10090]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4mngb_
  • Chain 'C':
    Compound: Cd1d1 protein
    Species: Mus musculus [TaxId:10090]
    Gene: Cd1d1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15813 (Start-183)
    • Uniprot Q7TMK5 (184-277)
      • expression tag (278)
    Domains in SCOPe 2.07: d4mngc1, d4mngc2, d4mngc3
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Mus musculus [TaxId:10090]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4mngd_
  • Chain 'E':
    Compound: TRA@ protein,TRA@ protein, Ti antigen CD3-associated protein gamma chain V-J-C region
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6PJ56 (Start-118)
      • conflict (96-99)
      • conflict (101-102)
      • conflict (104-106)
    • PDB 4MNG
    Domains in SCOPe 2.07: d4mnge1, d4mnge2
  • Chain 'F':
    Compound: TRA@ protein,TRA@ protein, Ti antigen CD3-associated protein gamma chain V-J-C region
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6PJ56 (Start-118)
      • conflict (96-99)
      • conflict (101-102)
      • conflict (104-106)
    • PDB 4MNG
    Domains in SCOPe 2.07: d4mngf1, d4mngf2
  • Heterogens: NAG, CIS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mngA (A:)
adpvpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfs
dqqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafq
gkdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgks
elkkqekpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpna
detwylqatldveageeaglacrvkhsslggqdiilywsgr

    Sequence, based on observed residues (ATOM records): (download) 
    >4mngA (A:)
rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqe
kpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpnadetwyl
qatldveageeaglacrvkhsslggqdiilyws

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4mngB (B:)
iqktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskdw
sfyilahteftptetdtyacrvkhasmaepktvywdrdm

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4mngC (C:)
adpvpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfs
dqqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafq
gkdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgks
elkkqekpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpna
detwylqatldveageeaglacrvkhsslggqdiilywsgr

    Sequence, based on observed residues (ATOM records): (download) 
    >4mngC (C:)
rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqe
kpvawlssvpssahghrqlvchvsgfypkpvwvmwmrgdqeqqgthrgdflpnadetwyl
qatldveageeaglacrvkhsslggqdiilyws

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4mngD (D:)
iqktpqiqvysrhppengkpnilncyvtqfhpphieiqmlkngkkipkvemsdmsfskdw
sfyilahteftptetdtyacrvkhasmaepktvywdrdm

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4mngE (E:)
aqkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaks
grysvnfkkaaksvaltisalqledsakyfcalgepsywgfprttrvifgkgtrvtvepg
gggsggggsggggsggggsssnlegrtksvirqtgssaeitcdlaegstgyihwylhqeg
kapqrllyydsytssvvlesgispgkydtygstrknlrmilrnliendsgvyycatwdek
yykklfgsgtkliitdaasgad

    Sequence, based on observed residues (ATOM records): (download) 
    >4mngE (E:)
qkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaksg
rysvnfkkaaksvaltisalqledsakyfcalgepsywgfprttrvifgkgtrvtveptk
svirqtgssaeitcdlaegstgyihwylhqegkapqrllyydsytssvvlesgispgkyd
tygstrknlrmilrnliendsgvyycatwdekyykklfgsgtkliitd

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4mngF (F:)
aqkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaks
grysvnfkkaaksvaltisalqledsakyfcalgepsywgfprttrvifgkgtrvtvepg
gggsggggsggggsggggsssnlegrtksvirqtgssaeitcdlaegstgyihwylhqeg
kapqrllyydsytssvvlesgispgkydtygstrknlrmilrnliendsgvyycatwdek
yykklfgsgtkliitdaasgad

    Sequence, based on observed residues (ATOM records): (download) 
    >4mngF (F:)
qkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaksg
rysvnfkkaaksvaltisalqledsakyfcalgepsywgfprttrvifgkgtrvtveptk
svirqtgssaeitcdlaegstgyihwylhqegkapqrllyydsytssvvlesgispgkyd
tygstrknlrmilrnliendsgvyycatwdekyykklfgsgtkliitd