PDB entry 4lnx

View 4lnx on RCSB PDB site
Description: Crystal structure of TR-alpha bound to T4 in a second site
Class: transcription
Keywords: Mainly Alpha Orthogonal Bundle, Transcription factor, TRANSCRIPTION
Deposited on 2013-07-12, released 2014-03-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.157
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thyroid hormone receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10827 (4-End)
      • expression tag (1-3)
    Domains in SCOPe 2.08: d4lnxa1, d4lnxa2
  • Heterogens: T44, T3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lnxA (A:)
gshmeemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivs
mpdgdkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslra
avrydpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavl
lmstdrsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachas
rflhmkvecptelfpplflevfedqev

    Sequence, based on observed residues (ATOM records): (download) 
    >4lnxA (A:)
shmeemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivsm
pdgdkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslraa
vrydpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavll
mstdrsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachasr
flhmkvecptelfpplflevfed