SCOPe 2.08: Domain d4lnxa1: 4lnx A:148-407

Lineage for d4lnxa1 (4lnx A:148-407)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Thyroid hormone receptor alpha1 (TR-alpha1) [48532] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88962] (5 PDB entries)

8. Domain d4lnxa1: 4lnx A:148-407 [237837]
   Other proteins in same PDB: d4lnxa2
   automated match to d3jzba_
   complexed with t3, t44

Details for d4lnxa1

PDB Entry: 4lnx, 2.05 Å

PDB Description: Crystal structure of TR-alpha bound to T4 in a second site

PDB Compounds: (A:) Thyroid hormone receptor alpha

SCOPe Domain Sequences for d4lnxa1:

Sequence; same for both SEQRES and ATOM records:

>d4lnxa1 a.123.1.1 (A:148-407) Thyroid hormone receptor alpha1 (TR-alpha1) {Human (Homo sapiens) [TaxId: 9606]}
eemirslqqrpeptpeewdlihiateahrstnaqgshwkqrrkflpddigqspivsmpdg
dkvdleafseftkiitpaitrvvdfakklpmfselpcedqiillkgccmeimslraavry
dpesdtltlsgemavkreqlkngglgvvsdaifelgkslsafnlddtevallqavllmst
drsgllcvdkieksqeayllafehyvnhrkhniphfwpkllmkvtdlrmigachasrflh
mkvecptelfpplflevfed

Timeline for d4lnxa1:

• d4lnxa1 first appeared in SCOPe 2.03, called d4lnxa_
  
• d4lnxa1 appears in SCOPe 2.07