PDB entry 4l5m

View 4l5m on RCSB PDB site
Description: Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5
Class: signaling protein/inhibitor
Keywords: sec-7domain, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2013-06-11, released 2013-10-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-11-06, with a file datestamp of 2013-11-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.138
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytohesin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: CYTH2, ARNO, PSCD2, PSCD2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99418 (21-End)
      • expression tag (19-20)
    Domains in SCOPe 2.07: d4l5ma1, d4l5ma2
  • Heterogens: PO4, HRC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4l5mA (A:)
mgsshhhhhhssglvprgshmsktlqrnrkmamgrkkfnmdpkkgiqflvenellqntpe
eiarflykgeglnktaigdylgereelnlavlhafvdlheftdlnlvqalrqflwsfrlp
geaqkidrmmeafaqryclcnpgvfqstdtcyvlsfavimlntslhnpnvrdkpglerfv
amnrgineggdlpeellrnlydsirnepfkipeddgn

    Sequence, based on observed residues (ATOM records): (download) 
    >4l5mA (A:)
hmsktlqrnrkmamgrkkfnmdpkkgiqflvenellqntpeeiarflykgeglnktaigd
ylgereelnlavlhafvdlheftdlnlvqalrqflwsfrlpgeaqkidrmmeafaqrycl
cnpgvfqstdtcyvlsfavimlntslhnpnvrdkpglerfvamnrgineggdlpeellrn
lydsirnepfkipedd