PDB entry 4k60

View 4k60 on RCSB PDB site
Description: Crystal Structure of Human Chymase in Complex with Fragment 6-bromo-1,3-dihydro-2H-indol-2-one
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, glycosylated, Mast cells, secreted, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2013-04-15, released 2013-05-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chymase
    Species: Homo sapiens [TaxId:9606]
    Gene: CMA1, CYH, CYM
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23946 (0-225)
      • conflict (190)
      • conflict (215)
    Domains in SCOPe 2.08: d4k60a_
  • Heterogens: NAG, ZN, 1P8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k60A (A:)
iiggteckphsrpymayleivtsngpskfcggflirrnfvltaahcagrsitvtlgahni
teeedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlpfpsqknfvppg
rmcrvagwgrtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktksafkg
dsggpllcagaaqgivsygrsdakppavftrishyqpwinqilqan

    Sequence, based on observed residues (ATOM records): (download) 
    >4k60A (A:)
iiggteckphsrpymayleivtngpskfcggflirrnfvltaahcagrsitvtlgahnit
eeedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlpfvppgrmcrvag
wgrtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktksafkgdsggpll
cagaaqgivsygrsdakppavftrishyqpwinqilqan