PDB entry 4k43

View 4k43 on RCSB PDB site
Description: Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]
Class: contractile protein
Keywords: cell motility, gelsolin, CONTRACTILE PROTEIN
Deposited on 2013-04-11, released 2014-10-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-08, with a file datestamp of 2014-10-03.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.225
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4k43a1, d4k43a2
  • Chain 'B':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4k43b1, d4k43b2
  • Heterogens: CA, ADP, 1PO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k43A (A:)
dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
eydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4k43A (A:)
ttalvcdngsglvkagfagddapravfpsivgrpqkdsyvgdeaqskrgiltlkypiehg
iitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyv
aiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilt
ergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitigner
frcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmq
keitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4k43B (B:)
dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
eydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4k43B (B:)
ttalvcdngsglvkagfagddapravfpsivgrpqkdsyvgdeaqskrgiltlkypiehg
iitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyv
aiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilt
ergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitigner
frcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmq
keitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkc