PDB entry 4k2y

View 4k2y on RCSB PDB site
Description: Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-1,3-dihydro-2H-indol-2-one
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, glycosylated, Mast cells, secreted, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2013-04-09, released 2013-05-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chymase
    Species: Homo sapiens [TaxId:9606]
    Gene: CMA1, CYH, CYM
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23946 (0-225)
      • conflict (190)
      • conflict (215)
    Domains in SCOPe 2.08: d4k2ya_
  • Heterogens: ZN, NAG, ES2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4k2yA (A:)
iiggteckphsrpymayleivtsngpskfcggflirrnfvltaahcagrsitvtlgahni
teeedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlpfpsqknfvppg
rmcrvagwgrtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktksafkg
dsggpllcagaaqgivsygrsdakppavftrishyqpwinqilqan

    Sequence, based on observed residues (ATOM records): (download) 
    >4k2yA (A:)
iiggteckphsrpymayleivtsngpskfcggflirrnfvltaahcagrsitvtlgahni
teeedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlppgrmcrvagwg
rtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktksafkgdsggpllca
gaaqgivsygrsdakppavftrishyqpwinqilqan