PDB entry 4jmo

View 4jmo on RCSB PDB site
Description: Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Class: signaling protein/inhibitor
Keywords: Nucleotide exchange factor, ARF1, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2013-03-14, released 2013-10-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-04-23, with a file datestamp of 2014-04-18.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.155
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytohesin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: CYTH2, ARNO, PSCD2, PSCD2L
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99418 (4-End)
      • expression tag (2-3)
    Domains in SCOPe 2.07: d4jmoa1, d4jmoa2
  • Heterogens: JAF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4jmoA (A:)
    gshmsktlqrnrkmamgrkkfnmdpkkgiqflvenellqntpeeiarflykgeglnktai
    gdylgereelnlavlhafvdlheftdlnlvqalrqflwsfrlpgeaqkidrmmeafaqry
    clcnpgvfqstdtcyvlsfavimlntslhnpnvrdkpglerfvamnrgineggdlpeell
    rnlydsirnepfkipeddgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >4jmoA (A:)
    hmsktlqrnrkmamgrkkfnmdpkkgiqflvenellqntpeeiarflykgeglnktaigd
    ylgereelnlavlhafvdlheftdlnlvqalrqflwsfrlpgeaqkidrmmeafaqrycl
    cnpgvfqstdtcyvlsfavimlntslhnpnvrdkpglerfvamnrgineggdlpeellrn
    lydsirnepfkip