PDB entry 4iye

View 4iye on RCSB PDB site
Description: Crystal structure of AdTx1 (rho-Da1a) from eastern green mamba (Dendroaspis angusticeps)
Class: toxin
Keywords: Snake three-finger toxin family, Type A muscarinic toxin subfamily, Allosteric antagonist of the alpha-1A adrenergic receptor (ADRA1A), Acts as a relaxant of smooth muscle, alpha-1A adrenergic receptor, g-rhoDa1a K34A, Expressed by the venom gland, TOXIN
Deposited on 2013-01-28, released 2013-05-08
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-08-28, with a file datestamp of 2013-08-23.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.174
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toxin AdTx1
    Species: Dendroaspis angusticeps [TaxId:8618]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P85092 (1-65)
      • expression tag (0)
      • engineered mutation (34)
    Domains in SCOPe 2.04: d4iyea_
  • Heterogens: EDO, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4iyeA (A:)
    gltcvtsksifgittedcpdgqnlcfkrrhyvvpaiydstrgcaatcpipenydsihcck
    tdkcne