PDB entry 4iyc

View 4iyc on RCSB PDB site
Description: Structure of the T244A mutant of the PANTON-VALENTINE LEUCOCIDIN component from STAPHYLOCOCCUS AUREUS
Class: toxin
Keywords: Staphylococcus aureus, S component leucocidin, bi-component leucotoxin, beta-barrel pore forming toxin, TOXIN
Deposited on 2013-01-28, released 2014-01-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-23, with a file datestamp of 2014-04-18.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.198
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4iyca_
  • Chain 'B':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O80066 (Start-291)
      • engineered mutation (251)
    Domains in SCOPe 2.06: d4iycb_
  • Chain 'C':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O80066 (Start-291)
      • engineered mutation (251)
    Domains in SCOPe 2.06: d4iycc_
  • Chain 'D':
    Compound: LukS-PV
    Species: Staphylococcus phage PVL [TaxId:71366]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O80066 (Start-291)
      • engineered mutation (251)
    Domains in SCOPe 2.06: d4iycd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iycA (A:)
gplgspefdnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqg
finskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyn
iggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsg
hdpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygr
nmdvthatrrtahygnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4iycA (A:)
nnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyy
nykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgp
gngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpy
sqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrtg
nsylegsrihnafvnrnytvkyevnwktheikvkghn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4iycB (B:)
gplgspefdnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqg
finskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyn
iggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsg
hdpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygr
nmdvthatrrtahygnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4iycB (B:)
nnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyy
nykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgp
ssfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpysq
nprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrtahy
gnsylegsrihnafvnrnytvkyevnwktheikvkghn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4iycC (C:)
gplgspefdnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqg
finskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyn
iggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsg
hdpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygr
nmdvthatrrtahygnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4iycC (C:)
nienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyyn
ykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgps
tggsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpy
sqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrta
hygnsylegsrihnafvnrnytvkyevnwktheikvkghn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4iycD (D:)
gplgspefdnnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqg
finskttyynykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyn
iggnfnsgpstggngsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsg
hdpnlfvgykpysqnprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygr
nmdvthatrrtahygnsylegsrihnafvnrnytvkyevnwktheikvkghn

    Sequence, based on observed residues (ATOM records): (download) 
    >4iycD (D:)
nnienigdgaevvkrtedtssdkwgvtqniqfdfvkdkkynkdalilkmqgfinskttyy
nykntdhikamrwpfqyniglktndpnvdlinylpknkidsvnvsqtlgyniggnfnsgn
gsfnysktisynqqnyisevehqnsksvqwgikansfitslgkmsghdpnlfvgykpysq
nprdyfvpdnelpplvhsgfnpsfiatvshekgsgdtsefeitygrnmdvthatrrtahy
gnsylegsrihnafvnrnytvkyevnwktheikvkghn