PDB entry 4ixg

View 4ixg on RCSB PDB site
Description: pcDHFR-268-K37S-N69F variant
Class: OXIDOREDUCTASE/Inhibitor
Keywords: dihydrofolate reductase inhibitor ternary complex double variant, reductase, OXIDOREDUCTASE-Inhibitor complex
Deposited on 2013-01-25, released 2013-05-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'X':
  Compound: dihydrofolate reductase
  Species: Pneumocystis carinii [TaxId:4754]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P16184 (0-205)
    • engineered mutation (36)
    • engineered mutation (68)
  Domains in SCOPe 2.07: d4ixgx_
• Heterogens: NDP, IXG, HOH

PDB Chain Sequences:

• Chain 'X':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4ixgX (X:)
  mnqqksltlivalttsygigrsnslpwklkkeisyfsrvtsfvptfdsfesmnvvlmgrk
  twesiplqnrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinri
  fviggaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdlesw
  vgtkvphgkinedgfdyefemwtrdl