PDB entry 4ixe

View 4ixe on RCSB PDB site
Description: pcDHFR-NADPH-270
Class: OXIDOREDUCTASE/Inhibitor
Keywords: dihydrofolate reductase inhibitor cofactor ternary complex, reductase, OXIDOREDUCTASE-Inhibitor complex
Deposited on 2013-01-25, released 2013-05-29
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: 0.179
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: dihydrofolate reductase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ixed_
  • Heterogens: IXE, NDP, HOH

PDB Chain Sequences:

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4ixeD (D:)
mnqqksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrk
twesiplqfrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinri
fviggaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdlesw
vgtkvphgkinedgfdyefemwtrdl