PDB entry 4i6w

View 4i6w on RCSB PDB site
Description: 3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate
Class: Oxidoreductase
Keywords: Oxidoreductase
Deposited on 2012-11-30, released 2013-07-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-08-07, with a file datestamp of 2013-08-02.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: 0.194
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4i6wa1, d4i6wa2
  • Chain 'B':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4i6wb1, d4i6wb2
  • Heterogens: 1CO, SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i6wA (A:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4i6wA (A:)
ldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpy
avasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiq
dplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvr
damgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsge
aviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghyg
slttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgl
aqnlgamralate

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i6wB (B:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >4i6wB (B:)
ldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpy
avasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiq
dplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvr
damgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsge
aviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghyg
slttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgl
aqnlgamralategiq