PDB entry 4i6n

View 4i6n on RCSB PDB site
Description: Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester
Class: Hydrolase/Signaling Protein
Keywords: helix-beta-helix sandwich, protein-protein complex, deubiquitination, ubiquitin c-terminal hydrolase, cytosol, Hydrolase-Signaling Protein complex
Deposited on 2012-11-29, released 2013-05-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-05-29, with a file datestamp of 2013-05-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.176
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-hydrolase
    Species: Trichinella spiralis [TaxId:6334]
    Database cross-references and differences (RAF-indexed):
    • PDB 4I6N
    Domains in SCOPe 2.07: d4i6na1, d4i6na2
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4i6nb_
  • Chain 'C':
    Compound: Ubiquitin carboxyl-hydrolase
    Species: Trichinella spiralis [TaxId:6334]
    Database cross-references and differences (RAF-indexed):
    • PDB 4I6N
    Domains in SCOPe 2.07: d4i6nc1, d4i6nc2
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4i6nd_
  • Heterogens: DTT, NA, GVE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4i6nA (A:)
    gplgsmaegnwcliesdpgiftemihgfgctglqveelvvldesiehlkpihgfiflfrw
    lkkemrkevddspqtctdvyfsqqviqnacasqalinlllncdhpdvdlgptlkefkdft
    ydldsasrglcltnsekiravhnsfgrqqlfeiddqqkldeedvfhfvtyvpvndgvyel
    dglraaplrlgtvasdgdwtevaikaikekiknygesevrfnlmavisdqk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4i6nA (A:)
    plgsmaegnwcliesdpgiftemihgfgctglqveelvvldesiehlkpihgfiflfrwl
    kkemrkevddspqtctdvyfsqqviqnacasqalinlllncdhpdvdlgptlkefkdfty
    dldsasrglcltnsekiravhnsfgqkldeedvfhfvtyvpvndgvyeldglraaplrlg
    tvasdgdwtevaikaikekiknygesevrfnlmavisdq
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i6nB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4i6nC (C:)
    gplgsmaegnwcliesdpgiftemihgfgctglqveelvvldesiehlkpihgfiflfrw
    lkkemrkevddspqtctdvyfsqqviqnacasqalinlllncdhpdvdlgptlkefkdft
    ydldsasrglcltnsekiravhnsfgrqqlfeiddqqkldeedvfhfvtyvpvndgvyel
    dglraaplrlgtvasdgdwtevaikaikekiknygesevrfnlmavisdqk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4i6nC (C:)
    plgsmaegnwcliesdpgiftemihgfgctglqveelvvldesiehlkpihgfiflfrwl
    kkemrkevddspqtctdvyfsqqviqnacasqalinlllncdhpdvdlgptlkefkdfty
    dldsasrglcltnsekiravhnsfgkldeedvfhfvtyvpvndgvyeldglraaplrlgt
    vasdgdwtevaikaikekiknygesevrfnlmavisd
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4i6nD (D:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrg