PDB entry 4h5x

View 4h5x on RCSB PDB site
Description: human Plk1-PBD with a glycerol bound at the phophopeptide binding site
Class: transferase
Keywords: Kinase, TRANSFERASE
Deposited on 2012-09-19, released 2012-10-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-03-06, with a file datestamp of 2013-03-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.2
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4h5xa1, d4h5xa2
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4h5xb1, d4h5xb2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h5xA (A:)
snagevvdchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkygl
gyqlcdnsvgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfr
nymsehllkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklil
cplmaavtyidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnrlkas

    Sequence, based on observed residues (ATOM records): (download) 
    >4h5xA (A:)
chlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdns
vgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehll
kaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavt
yidekrdfrtyrlslleeygcckelasrlryartmvdkllss

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h5xB (B:)
snagevvdchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkygl
gyqlcdnsvgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfr
nymsehllkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklil
cplmaavtyidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnrlkas

    Sequence, based on observed residues (ATOM records): (download) 
    >4h5xB (B:)
dchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdn
svgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehl
lkaganitprrlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidek
rdfrtyrlslleeygcckelasrlryartmvdkllssr