PDB entry 4h4g

View 4h4g on RCSB PDB site
Description: Crystal Structure of (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase from Burkholderia thailandensis E264
Class: lyase
Keywords: Structural Genomics, NIAID, National Institute of Allergy and Infectious Diseases, Seattle Structural Genomics Center for Infectious Disease, SSGCID, Lipid A biosynthesis, Lipid synthesis, hydrolyase enzyme, LYASE
Deposited on 2012-09-17, released 2012-10-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.187
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4ga_
  • Chain 'B':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gb_
  • Chain 'C':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gc_
  • Chain 'D':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gd_
  • Chain 'E':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4ge_
  • Chain 'F':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gf_
  • Chain 'G':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gg_
  • Chain 'H':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gh_
  • Chain 'I':
    Compound: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: fabZ, BTH_I2038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4h4gi_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h4gA (A:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gA (A:)
fdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvlii
ealaqaaalltfaealyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkavaevd
gkvaaeaelmctvkt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h4gB (B:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gB (B:)
nfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvli
iealaqaaalltfaeafvgidnarfkrvvepgdqlilnvtferywkfkavaevdgkvaae
aelmc

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4h4gC (C:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gC (C:)
nfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvli
iealaqaaalltfaeatlyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkavae
vdgkvaaeaelmctvkt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4h4gD (D:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gD (D:)
fdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvlii
ealaqaaalltfaeapentlyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkav
aevdgkvaaeaelmctvkt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4h4gE (E:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gE (E:)
tekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmp
gvliiealaqaaalltfalyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkava
evdgkvaaeaelmctvk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4h4gF (F:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gF (F:)
infdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvl
iiealaqaaalltfaeatlyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkava
evdgkvaaeaelmctvkt

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4h4gG (G:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gG (G:)
infdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvl
iiealaqaaalltfaeatlyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkava
evdgkvaaeaelmctvkt

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4h4gH (H:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gH (H:)
nfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgvli
iealaqaaalltfayyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkavaevdgk
vaaeaelmctvk

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >4h4gI (I:)
mrrtimstekinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghf
pkrpvmpgvliiealaqaaalltfaeaepkdpentlyyfvgidnarfkrvvepgdqliln
vtferyirgiwkfkavaevdgkvaaeaelmctvktadaap

    Sequence, based on observed residues (ATOM records): (download) 
    >4h4gI (I:)
kinfdihkiltllphrypillvdrvlelephksikalknvtvnepfftghfpkrpvmpgv
liiealaqaaalltfaelyyfvgidnarfkrvvepgdqlilnvtferyirgiwkfkavae
vdgkvaaeaelmctvk