PDB entry 4h2h

View 4h2h on RCSB PDB site
Description: Crystal structure of an enolase (mandalate racemase subgroup, target EFI-502101) from Pelagibaca bermudensis htcc2601, with bound mg and l-4-hydroxyproline betaine (betonicine)
Class: isomerase
Keywords: Enolase, mandelate racemase subgroup, enzyme function initiative, EFI, Structural Genomics, ISOMERASE
Deposited on 2012-09-12, released 2012-10-10
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-11-06, with a file datestamp of 2013-11-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.16
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (8-9)
    Domains in SCOPe 2.03: d4h2ha1, d4h2ha2
  • Chain 'B':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
    Domains in SCOPe 2.03: d4h2hb1, d4h2hb2
  • Chain 'C':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
    Domains in SCOPe 2.03: d4h2hc1, d4h2hc2
  • Chain 'D':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
  • Chain 'E':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
  • Chain 'F':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
  • Chain 'G':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
  • Chain 'H':
    Compound: Mandelate racemase/muconate lactonizing enzyme
    Species: Pelagibaca bermudensis [TaxId:314265]
    Gene: R2601_01638
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0FPQ4 (10-375)
      • expression tag (9)
  • Heterogens: MG, NI, 0XW, IOD, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h2hA (A:)
mahhhhhhslkiaeiqlfqhdlpvvngpyriasgdvwsltttivkiiaedgtigwgetcp
vgptyaeahaggalaalevlasglagaealplplhtrmdsllcghnyaksaldiavhdlw
gkrlgvpvhellggaltdsvssyyslgvmepdeaarqalekqregysrlqvklgarpiei
dieairkvweavrgtgialaadgnrgwttrdalrfsrecpdipfvmeqpcnsfedleair
plchhalymdedgtslntvitaaatslvdgfgmkvsrigglqhmrafrdfcaarnlphtc
ddawggdivsaacthiastvlprlmegawlaqpyvaehydaengvrieggrirvpqgpgl
gltidperfgpplfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4h2hA (A:)
slkiaeiqlfqhdlpvvngpyriasgdvwsltttivkiiaedgtigwgetcpvgptyaea
haggalaalevlasglagaealplplhtrmdsllcghnyaksaldiavhdlwgkrlgvpv
hellggaltdsvssyyslgvmepdeaarqalekqregysrlqvklgarpieidieairkv
weavrgtgialaadgnrgwttrdalrfsrecpdipfvmeqpcnsfedleairplchhaly
mdedgtslntvitaaatslvdgfgmkvsrigglqhmrafrdfcaarnlphtcddawggdi
vsaacthiastvlprlmegawlaqpyvaehydaengvrieggrirvpqgpglgltidper
fgpplfsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h2hB (B:)
mahhhhhhslkiaeiqlfqhdlpvvngpyriasgdvwsltttivkiiaedgtigwgetcp
vgptyaeahaggalaalevlasglagaealplplhtrmdsllcghnyaksaldiavhdlw
gkrlgvpvhellggaltdsvssyyslgvmepdeaarqalekqregysrlqvklgarpiei
dieairkvweavrgtgialaadgnrgwttrdalrfsrecpdipfvmeqpcnsfedleair
plchhalymdedgtslntvitaaatslvdgfgmkvsrigglqhmrafrdfcaarnlphtc
ddawggdivsaacthiastvlprlmegawlaqpyvaehydaengvrieggrirvpqgpgl
gltidperfgpplfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4h2hB (B:)
lkiaeiqlfqhdlpvvngpyriasgdvwsltttivkiiaedgtigwgetcpvgptyaeah
aggalaalevlasglagaealplplhtrmdsllcghnyaksaldiavhdlwgkrlgvpvh
ellggaltdsvssyyslgvmepdeaarqalekqregysrlqvklgarpieidieairkvw
eavrgtgialaadgnrgwttrdalrfsrecpdipfvmeqpcnsfedleairplchhalym
dedgtslntvitaaatslvdgfgmkvsrigglqhmrafrdfcaarnlphtcddawggdiv
saacthiastvlprlmegawlaqpyvaehydaengvrieggrirvpqgpglgltidperf
gpplfsa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4h2hC (C:)
mahhhhhhslkiaeiqlfqhdlpvvngpyriasgdvwsltttivkiiaedgtigwgetcp
vgptyaeahaggalaalevlasglagaealplplhtrmdsllcghnyaksaldiavhdlw
gkrlgvpvhellggaltdsvssyyslgvmepdeaarqalekqregysrlqvklgarpiei
dieairkvweavrgtgialaadgnrgwttrdalrfsrecpdipfvmeqpcnsfedleair
plchhalymdedgtslntvitaaatslvdgfgmkvsrigglqhmrafrdfcaarnlphtc
ddawggdivsaacthiastvlprlmegawlaqpyvaehydaengvrieggrirvpqgpgl
gltidperfgpplfsa

    Sequence, based on observed residues (ATOM records): (download) 
    >4h2hC (C:)
lkiaeiqlfqhdlpvvngpyriasgdvwsltttivkiiaedgtigwgetcpvgptyaeah
aggalaalevlasglagaealplplhtrmdsllcghnyaksaldiavhdlwgkrlgvpvh
ellggaltdsvssyyslgvmepdeaarqalekqregysrlqvklgarpieidieairkvw
eavrgtgialaadgnrgwttrdalrfsrecpdipfvmeqpcnsfedleairplchhalym
dedgtslntvitaaatslvdgfgmkvsrigglqhmrafrdfcaarnlphtcddawggdiv
saacthiastvlprlmegawlaqpyvaehydaengvrieggrirvpqgpglgltidperf
gpplfsa

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.