PDB entry 4gx4

View 4gx4 on RCSB PDB site
Description: AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with mutation R22M
Class: hydrolase
Keywords: allosteric enzymes, cooperativity, oligomerization, HYDROLASE
Deposited on 2012-09-03, released 2013-09-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.216
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-1,6-bisphosphatase 1
    Species: Sus scrofa [TaxId:9823]
    Gene: FBP, FBP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00636
      • engineered mutation (21)
    Domains in SCOPe 2.06: d4gx4a_
  • Chain 'B':
    Compound: Fructose-1,6-bisphosphatase 1
    Species: Sus scrofa [TaxId:9823]
    Gene: FBP, FBP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00636
      • engineered mutation (21)
    Domains in SCOPe 2.06: d4gx4b_
  • Heterogens: F6P, MG, AMP, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gx4A (A:)
tdqaafdtnivtltrfvmeegmkargtgemtqllnslctavkaistavrkagiahlygia
gstnvtgdqvkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdpl
dgssnidclvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvng
vncfmldpaigefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapy
garyvgsmvadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgke
avldivptdihqrapiilgspedvtelleiyqkhaak

    Sequence, based on observed residues (ATOM records): (download) 
    >4gx4A (A:)
nivtltrfvmeegmkargtgemtqllnslctavkaistavrkagiahlygiagstnvtgd
qvkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdpldgssnidc
lvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvngvncfmldp
aigefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapygaryvgsm
vadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgkeavldivpt
dihqrapiilgspedvtelleiyqkha

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4gx4B (B:)
tdqaafdtnivtltrfvmeegmkargtgemtqllnslctavkaistavrkagiahlygia
gstnvtgdqvkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdpl
dgssnidclvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvng
vncfmldpaigefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapy
garyvgsmvadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgke
avldivptdihqrapiilgspedvtelleiyqkhaak

    Sequence, based on observed residues (ATOM records): (download) 
    >4gx4B (B:)
nivtltrfvmeegmkargtgemtqllnslctavkaistavrkagiahlygiagstnvtgd
qvkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdpldgssnidc
lvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvngvncfmldp
aigefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapygaryvgsm
vadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgkeavldivpt
dihqrapiilgspedvtelleiyqkha