PDB entry 4gro

View 4gro on RCSB PDB site
Description: Crystallographic and biological characterization of N- and C- terminus mutants of human MIF
Class: cytokine, Isomerase
Keywords: alpha/beta mixture, cytokine, Isomerase
Deposited on 2012-08-26, released 2013-10-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-02, with a file datestamp of 2014-03-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.189
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4groa_
• Chain 'B':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4grob_
• Chain 'C':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4groc_
• Chain 'D':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4grod_
• Chain 'E':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4groe_
• Chain 'F':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4grof_
• Chain 'G':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4grog_
• Chain 'H':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: GLIF, MIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-116)
    • insertion (1-3)
  Domains in SCOPe 2.06: d4groh_
• Heterogens: CL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groA (A:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groB (B:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groC (C:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groD (D:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groE (E:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groF (F:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'G':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groG (G:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4groH (H:)
  paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
  lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa