PDB entry 4gqg

View 4gqg on RCSB PDB site
Description: Crystal structure of AKR1B10 complexed with NADP+
Class: oxidoreductase
Keywords: alpha-beta TIM barrel, NADP-dependant oxidoreductase, NADP+, OXIDOREDUCTASE
Deposited on 2012-08-23, released 2013-08-28
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-12-11, with a file datestamp of 2013-12-06.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: 0.184
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member B10
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B10
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60218 (2-317)
      • expression tag (0-1)
      • see remark 999 (314)
    Domains in SCOPe 2.04: d4gqga_
  • Heterogens: NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4gqgA (A:)
shmatfvelstkakmpivglgtwksplgkvkeavkvaidagyrhidcayvyqnehevgea
iqekiqekavkredlfivsklwptfferplvrkafektlkdlklsyldvylihwpqgfks
gddlfpkddkgnaiggkatfldaweameelvdeglvkalgvsnfshfqiekllnkpglky
kpvtnqvechpyltqekliqychskgitvtaysplgspdrpwakpedpslledpkikeia
akhkktaaqvlirfhiqrnvivipksvtpariveniqvfdfklsdeematilsfnrnwra
cnvlqsshledypfdaey