PDB entry 4gcy

View 4gcy on RCSB PDB site
Description: Structure of Mycobacterium tuberculosis dUTPase H21W mutant
Class: hydrolase
Keywords: jelly-roll, hydrolase
Deposited on 2012-07-31, released 2013-07-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-07-03, with a file datestamp of 2013-06-28.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.125
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: dut, Rv2697c, MT2771, MTCY05A6.18c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A552 (20-173)
      • expression tag (11-19)
      • engineered mutation (40)
    Domains in SCOPe 2.04: d4gcya_
  • Heterogens: DUP, TRS, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gcyA (A:)
mgsshhhhhhssglvprgshmsttlaivrldpglplpsrawdgdagvdlysaedvelapg
rralvrtgvavavpfgmvglvhprsglatrvglsivnspgtidagyrgeikvalinldpa
apivvhrgdriaqllvqrvelvelvevssfdeaglastsrgdgghgssgghasl

    Sequence, based on observed residues (ATOM records): (download) 
    >4gcyA (A:)
sglvprgshmsttlaivrldpglplpsrawdgdagvdlysaedvelapgrralvrtgvav
avpfgmvglvhprsglatrvglsivnspgtidagyrgeikvalinldpaapivvhrgdri
aqllvqrvelvelvevssfdeaglastsrgdgghgssgghasl