PDB entry 4em6

View 4em6 on RCSB PDB site
Description: The structure of Glucose-6-phosphate isomerase (GPI) from Brucella melitensis
Class: isomerase
Keywords: Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, SSGCID, Seattle Structural Genomics Center for Infectious Disease, NIAID, National Institute of Allergy and Infectious Diseases, isomerase
Deposited on 2012-04-11, released 2012-05-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-05-02, with a file datestamp of 2012-04-27.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.133
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucose-6-phosphate isomerase
    Species: Brucella melitensis bv. 1 [TaxId:224914]
    Gene: pgi, BMEI1636
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4em6a_
  • Chain 'B':
    Compound: Glucose-6-phosphate isomerase
    Species: Brucella melitensis bv. 1 [TaxId:224914]
    Gene: pgi, BMEI1636
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4em6b_
  • Chain 'C':
    Compound: Glucose-6-phosphate isomerase
    Species: Brucella melitensis bv. 1 [TaxId:224914]
    Gene: pgi, BMEI1636
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4em6c_
  • Chain 'D':
    Compound: Glucose-6-phosphate isomerase
    Species: Brucella melitensis bv. 1 [TaxId:224914]
    Gene: pgi, BMEI1636
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4em6d_
  • Heterogens: CL, CA, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4em6A (A:)
gpgsmardatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcr
vndetmallkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvl
pdvkhvldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdepr
ahfvsnidgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavga
hfaavstaldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagah
amdvhfrdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesng
ksvtldgkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqh
emlmanclaqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdml
dpytlgrlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdast
qglvahlharrka

    Sequence, based on observed residues (ATOM records): (download) 
    >4em6A (A:)
rdatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcrvndetm
allkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvlpdvkhv
ldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdeprahfvsn
idgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavgahfaavs
taldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagahamdvhf
rdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesngksvtld
gkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqhemlman
claqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdmldpytlg
rlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdastqglvah
lharrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4em6B (B:)
gpgsmardatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcr
vndetmallkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvl
pdvkhvldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdepr
ahfvsnidgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavga
hfaavstaldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagah
amdvhfrdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesng
ksvtldgkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqh
emlmanclaqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdml
dpytlgrlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdast
qglvahlharrka

    Sequence, based on observed residues (ATOM records): (download) 
    >4em6B (B:)
rdatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcrvndetm
allkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvlpdvkhv
ldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdeprahfvsn
idgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavgahfaavs
taldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagahamdvhf
rdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesngksvtld
gkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqhemlman
claqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdmldpytlg
rlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdastqglvah
lharrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4em6C (C:)
gpgsmardatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcr
vndetmallkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvl
pdvkhvldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdepr
ahfvsnidgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavga
hfaavstaldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagah
amdvhfrdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesng
ksvtldgkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqh
emlmanclaqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdml
dpytlgrlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdast
qglvahlharrka

    Sequence, based on observed residues (ATOM records): (download) 
    >4em6C (C:)
atkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcrvndetmal
lkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvlpdvkhvld
rmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdeprahfvsnid
gahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavgahfaavsta
ldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagahamdvhfrd
apleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesngksvtldgk
pvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqhemlmancl
aqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdmldpytlgrl
ialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdastqglvahlh
arrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4em6D (D:)
gpgsmardatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcr
vndetmallkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvl
pdvkhvldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdepr
ahfvsnidgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavga
hfaavstaldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagah
amdvhfrdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesng
ksvtldgkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqh
emlmanclaqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdml
dpytlgrlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdast
qglvahlharrka

    Sequence, based on observed residues (ATOM records): (download) 
    >4em6D (D:)
rdatkleatvaklkkhwaesaprdmraafsadpgrfgryslclddllfdwskcrvndetm
allkelavaadvegrraamfagehinntedravlhvalrdtsskevlvdghnvlpdvkhv
ldrmaafadgirsgalkgatgrkitdivnigiggsdlgpvmatlalapyhdeprahfvsn
idgahiadtlspldpastliivasktfttietmtnaqtarkwvadtlgeaavgahfaavs
taldkvaafgipedrvfgfwdwvggrysvwsaiglpvmiavgpdnfrkflagahamdvhf
rdapleknlpvmlgligywhraicgygsraiipydqrlsrlpaylqqldmesngksvtld
gkpvsgptgpvvwgepgtngqhaffqllhqgtdtiplefivaakgheptldhqhemlman
claqsealmkgrtldearaqlqaknlpasqveriaphrvfsgnrpsltlihdmldpytlg
rlialyehrvfveaqifginafdqwgvelgkelatellpvvsgkegasgrdastqglvah
lharrk