PDB entry 4edy
View 4edy on RCSB PDB site
Description: Crystal structure of hH-PGDS with water displacing inhibitor
Class: Isomerase/Isomerase inhibitor
Keywords: Inhibitor, Solvent replacement, Isomerase-Isomerase inhibitor complex
Deposited on
2012-03-27, released
2012-10-03
The last revision prior to the SCOPe 2.04 freeze date was dated
2013-01-02, with a file datestamp of
2012-12-28.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.176
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hematopoietic prostaglandin d synthase
Species: Homo sapiens [TaxId:9606]
Gene: GSTS, HPGDS, PGDS, PTGDS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4edya1, d4edya2 - Chain 'B':
Compound: hematopoietic prostaglandin d synthase
Species: Homo sapiens [TaxId:9606]
Gene: GSTS, HPGDS, PGDS, PTGDS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4edyb1, d4edyb2 - Heterogens: MG, GSH, 9PQ, DMS, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4edyA (A:)
hpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl
Sequence, based on observed residues (ATOM records): (download)
>4edyA (A:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipavanwikrrpqtkl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4edyB (B:)
hpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl
Sequence, based on observed residues (ATOM records): (download)
>4edyB (B:)
hpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaeqdvkeqmfnellty
naphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkvq
aipavanwikrrpqtkl