PDB entry 4ebc

View 4ebc on RCSB PDB site
Description: Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota
Class: transferase/DNA
Keywords: polymerase, TRANSFERASE-DNA complex
Deposited on 2012-03-23, released 2012-06-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-07-11, with a file datestamp of 2012-07-06.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.211
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase iota
    Species: Homo sapiens [TaxId:9606]
    Gene: POLI, RAD30B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4ebca1, d4ebca2
  • Chain 'P':
    Compound: 5'-d(p*ap*gp*gp*ap*cp*cp*(doc))-3'
  • Chain 'T':
    Compound: 5'-d(p*cp*tp*gp*gp*gp*tp*cp*cp*t)-3'
  • Heterogens: 0OH, CA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ebcA (A:)
meladvgaaassqgvhdqvlptpnassrvivhvdldcfyaqvemisnpelkdkplgvqqk
ylvvtcnyearklgvkklmnvrdakekcpqlvlvngedltryremsykvtelleefspvv
erlgfdenfvdltemvekrlqqlqsdelsavtvsghvynnqsinlldvlhirllvgsqia
aemreamynqlgltgcagvasnkllaklvsgvfkpnqqtvllpescqhlihslnhikeip
gigyktakclealginsvrdlqtfspkilekelgisvaqriqklsfgednspvilsgppq
sfseedsfkkcsseveaknkieellasllnrvcqdgrkphtvrliirryssekhygresr
qcpipshviqklgtgnydvmtpmvdilmklfrnmvnvkmpfhltllsvcfcnlkalntak

    Sequence, based on observed residues (ATOM records): (download) 
    >4ebcA (A:)
ssrvivhvdldcfyaqvemisnpelkdkplgvqqkylvvtcnyearklgvkklmnvrdak
ekcpqlvlvngedltryremsykvtelleefspvverlgfdenfvdltemvekrlqqlqs
delsavtvsghvynnqsinlldvlhirllvgsqiaaemreamynqlgltgcagvasnkll
aklvsgvfkpnqqtvllpescqhlihslnhikeipgigyktakclealginsvrdlqtfs
pkilekelgisvaqriqklsfgednspvilsgppqsfseedsfkkcsseveaknkieell
asllnrvcqdrkphtvrliirrygresrqcpipshviqkdvmtpmvdilmklfrnmvnvk
mpfhltllsvcfcnlk

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.