PDB entry 4dxw

View 4dxw on RCSB PDB site
Description: Crystal structure of NavRh, a voltage-gated sodium channel
Class: transport protein
Keywords: tetrameric, voltage-gated sodium channel, sodium selective, voltage-gated ion channel, TRANSPORT PROTEIN
Deposited on 2012-02-28, released 2012-05-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-07-10, with a file datestamp of 2013-07-05.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: 0.239
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ion transport protein
    Species: alpha proteobacterium HIMB114 [TaxId:684719]
    Gene: HIMB114_0051, HIMB114_1443
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0RMU8 (Start-227)
      • engineered mutation (207)
    Domains in SCOPe 2.07: d4dxwa_
  • Chain 'B':
    Compound: Ion transport protein
    Species: alpha proteobacterium HIMB114 [TaxId:684719]
    Gene: HIMB114_0051, HIMB114_1443
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0RMU8 (Start-227)
      • engineered mutation (207)
      • expression tag (228)
    Domains in SCOPe 2.07: d4dxwb1, d4dxwb2
  • Chain 'C':
    Compound: Ion transport protein
    Species: alpha proteobacterium HIMB114 [TaxId:684719]
    Gene: HIMB114_0051, HIMB114_1443
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0RMU8
      • engineered mutation (207)
    Domains in SCOPe 2.07: d4dxwc_
  • Chain 'D':
    Compound: Ion transport protein
    Species: alpha proteobacterium HIMB114 [TaxId:684719]
    Gene: HIMB114_0051, HIMB114_1443
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0RMU8
      • engineered mutation (207)
    Domains in SCOPe 2.07: d4dxwd_
  • Heterogens: BNG, CA, PX4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4dxwA (A:)
mtpffsslkdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieil
irfigekqkadffksgwnifdtvivaislipipnnssflvlrllrifrvlrlisvipelk
qiieailesvrrvffvslllfiilyiyatmgailfgnddpsrwgdlgislitlfqvltls
swetvmlpmqeiywwswvyffsfiiicsitilnlviailvdvviqkkle

    Sequence, based on observed residues (ATOM records): (download) 
    >4dxwA (A:)
tpffsslkdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieili
rfigsgwnifdtvivaislipvlrllrifrvlrlisvipelkqiieailesvrrvffvsl
llfiilyiyatmgailfgnddpsrwgdlgislitlfqvltlsswetvmlpmqeiywwswv
yffsfiiicsitilnlviailvdvviqkkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4dxwB (B:)
mtpffsslkdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieil
irfigekqkadffksgwnifdtvivaislipipnnssflvlrllrifrvlrlisvipelk
qiieailesvrrvffvslllfiilyiyatmgailfgnddpsrwgdlgislitlfqvltls
swetvmlpmqeiywwswvyffsfiiicsitilnlviailvdvviqkkle

    Sequence, based on observed residues (ATOM records): (download) 
    >4dxwB (B:)
ffsslkdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieilirf
igekqkasgwnifdtvivaislipipnnssflvlrllrifrvlrlisvipelkqiieail
esvrrvffvslllfiilyiyatmgailfgnddpsrwgdlgislitlfqvltlsswetvml
pmqeiywwswvyffsfiiicsitilnlviailvdvviqkkle

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4dxwC (C:)
mtpffsslkdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieil
irfigekqkadffksgwnifdtvivaislipipnnssflvlrllrifrvlrlisvipelk
qiieailesvrrvffvslllfiilyiyatmgailfgnddpsrwgdlgislitlfqvltls
swetvmlpmqeiywwswvyffsfiiicsitilnlviailvdvviqkkle

    Sequence, based on observed residues (ATOM records): (download) 
    >4dxwC (C:)
kdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieiligwnifdt
vivaislipsflvlrllrifrvlrlisvipelkqiieailesvrrvffvslllfiilyiy
atmgailfgnddpsrwgdlgislitlfqvltlsswetvmlpmqeiywwswvyffsfiiic
sitilnlviailvdvviqk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4dxwD (D:)
mtpffsslkdnrifqftvvsiiilnavligattyeldplfletihlldygitiffvieil
irfigekqkadffksgwnifdtvivaislipipnnssflvlrllrifrvlrlisvipelk
qiieailesvrrvffvslllfiilyiyatmgailfgnddpsrwgdlgislitlfqvltls
swetvmlpmqeiywwswvyffsfiiicsitilnlviailvdvviqkkle

    Sequence, based on observed residues (ATOM records): (download) 
    >4dxwD (D:)
fqftvvsiiilnavligeldplfletihlldygitiffvieilirfigwnifdtvivais
lipipnnssflvlrllrifrvlrlisvipelkqiieailesvrrvffvslllfiilyiya
tmgailfgnddpsrwgdlgislitlfqvltlsswetvmlpmqeiywwswvyffsfiiics
itilnlviailvdvviqkk