PDB entry 4dfy

View 4dfy on RCSB PDB site
Description: Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop
Class: transferase
Keywords: protein kinase fold, Serine/Threonine kinase activity, cAMP-dependent protein kinase regulatory subunit, PKI, phosphorylation, TRANSFERASE
Deposited on 2012-01-24, released 2012-02-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-16, with a file datestamp of 2012-05-11.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.253
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Mus musculus [TaxId:10090]
    Gene: Prkaca, Pkaca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4dfya_
  • Chain 'E':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Mus musculus [TaxId:10090]
    Gene: Prkaca, Pkaca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4dfye_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4dfyA (A:)
mgsshhhhhhssglvprgshmgnaaaakkgseqesvkeflakakedflkkwetpsqntaq
ldqfdriktlgtgsfgrvmlvkhkesgnhyamkildkqkvvklkqiehtlnekrilqavn
fpflvklefsfkdnsnlymvmeyvaggemfshlrrigrfsepharfyaaqivltfeylhs
ldliyrdlkpenllidqqgyiqvtdfgfakrvkgatwtlcgtpeylapeiilskgynkav
dwwalgvliyemaagyppffadqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltk
rfgnlkngvndiknhkwfattdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsi
nekcgkeftef

    Sequence, based on observed residues (ATOM records): (download) 
    >4dfyA (A:)
svkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfatpeyl
apeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsgkvrfpshfssdl
kdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveapfipkfeeirvsi
nekcgkeftef

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4dfyE (E:)
mgsshhhhhhssglvprgshmgnaaaakkgseqesvkeflakakedflkkwetpsqntaq
ldqfdriktlgtgsfgrvmlvkhkesgnhyamkildkqkvvklkqiehtlnekrilqavn
fpflvklefsfkdnsnlymvmeyvaggemfshlrrigrfsepharfyaaqivltfeylhs
ldliyrdlkpenllidqqgyiqvtdfgfakrvkgatwtlcgtpeylapeiilskgynkav
dwwalgvliyemaagyppffadqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltk
rfgnlkngvndiknhkwfattdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsi
nekcgkeftef

    Sequence, based on observed residues (ATOM records): (download) 
    >4dfyE (E:)
svkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfacgtpe
ylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsgkvrfpshfss
dlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveapfipkfeeirv
sinekcgkeftef