SCOPe 2.08: Domain d4dfya_: 4dfy A:

Lineage for d4dfya_ (4dfy A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein cAMP-dependent PK, catalytic subunit [56116] (7 species)
   AGC group; PKA subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56119] (33 PDB entries)

8. Domain d4dfya_: 4dfy A: [251437]
   automated match to d3qame_
   mutant

Details for d4dfya_

PDB Entry: 4dfy, 3 Å

PDB Description: Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop

PDB Compounds: (A:) cAMP-dependent protein kinase catalytic subunit alpha

SCOPe Domain Sequences for d4dfya_:

Sequence, based on SEQRES records:

>d4dfya_ d.144.1.7 (A:) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
svkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkg
atwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

Sequence, based on observed residues (ATOM records):

>d4dfya_ d.144.1.7 (A:) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
svkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfatpeyl
apeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsgkvrfpshfssdl
kdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveapfipkfeeirvsi
nekcgkeftef

Timeline for d4dfya_:

• d4dfya_ first appeared in SCOPe 2.04
  
• d4dfya_ appears in SCOPe 2.07